The church is located at 49 Park Street on the historic Guilford Green, minutes from exit 58 off Interstate 95. It is a branch church of The Mother Church, The First Church of Christ, Scientist in Boston Massachusetts.

The building was originally built as Third Congregational Church in 1850 by a group of abolitionists who broke away from First Church. It was the Parish House for Christ Episcopal Church and in the 30's and 40's it was a theater called The Chapel Playhouse.

In 1951, a small group of Christian Scientists bought the building, returning it to its original use as a church. It has been recently accepted into the Connecticut Historic Restoration Fund Matching Grant program for renovations.

The Sunday service consists of the weekly Bible Lesson Sermon read by lay people who have been elected from the membership. The lesson is a compilation of citations from The King James Version of The Bible and Science and Health with Key to the Scriptures by Mary Baker Eddy. These books have been designated as Pastor. The same lesson is heard in all Christian Science churches throughout the world and has been studied throughout the week by many of those who attend. Printed copies are available at any Christian Science Reading Room.

During the service, hymns are sung by the congregation and a solo is provided to tie in with the weekly subject. A collection is taken at the end of this service. Child care is provided for those too young to attend Sunday School or church services.

The Sunday Service is at 10:30 a.m.

The Christian Science Reading Room is located at 17 Whitfield Street, across the Guilford Green from the Church. It is a spiritual discovery center for all those seeking a closer relationship to God.